Editor’s Choice – Volume 17 N° 3
DSM-5 has excluded OCD and PTSD from its chapter on anxiety disorders. In this issue of Dialogues in Clinical Neuroscience, Guy Goodwin has reviewed the overlap between anxiety disorders, as defined by DSM-5, and dysphoria. The serotonin system and its connections, especially in the amygdala, provide a common nonspecific substrate both for disturbance and treatment effects.
Although SSRIs and SNRIs have been shown to be beneficial for the treatment of anxiety disorders, at least one third of the patients do not achieve an adequate clinical therapeutic response. Eduard Maron and David Nutt have looked at potential new biological predictors of pharmacological therapy of anxiety disorders.
Finally, Borwin Bandelow and Sophie Michaelis have examined the prevalence of anxiety disorders (up to 34% of the population during their lifetime) and have reported substantial under-recognition and under-treatment of these disorders.
September 2015 - Vol 17 - No. 3
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